16 Panel Drug Test Cups
A 16 panel drug test cup collects a urine sample and screens it for sixteen drugs at once, with results
in about 5 minutes. All seven of our Serenity Cup® 16 panel cups test the same twelve core drugs: AMP,
BAR, BUP, BZO, COC, fentanyl, MDMA, MET, MTD, OPI, OXY and PCP. The last four slots change from cup
to cup, choosing from THC, EtG (alcohol), tramadol, K2, TCA, kratom, ketamine and propoxyphene. Four cups
add adulterant checks. One cup is CLIA waived; the other six are labeled Forensic Use Only. Cups come in 120 mL
or a 90 mL economy size, from $1.69 per cup in bulk. Need fewer drugs? Our 12 panel drug test guide explains the classic panel.
Showing all 7 results
16 Panel Drug Test Detects Kratom, Alcohol, ETG, TCA and Fentanyl, As low as $2.09
AMP, BAR, BUP, BZO, COC, EtG, FEN, KRA, MDMA, MET, MTD, OPI/MOR, OXY, PCP, TCA, THCForensic UseAs low As$2.09 $2.09 - $3.29 — available on subscription
90ML Urine Test Cup 16 Panel with ETG, FEN, K2, TRA, KRA & Adulterants
ADLTX, AMP, BAR, BUP, BZO, COC, EtG, FEN, K2, KRA, MDMA, MET, MTD, OPI/MOR, OXY, PCP, TRAForensic UseAs low As$1.99 $1.99 - $3.29
90ML Urine Test Cup 16 Panel with ETG, FEN, K2, KET & Adulterants
ADLTX, AMP, BAR, BUP, BZO, COC, EtG, FEN, K2, KET, MDMA, MET, MTD, OPI/MOR, OXY, PCP, THCForensic UseAs low As$1.99 $1.99 - $3.29
16 Panel Drug Test Cup with Tramadol, Fentanyl, EtG & TCA, as Low as price $2.09
AMP, BAR, BUP, BZO, COC, EtG, FEN, MDMA, MET, MTD, OPI/MOR, OXY, PCP, TCA, THC, TRAForensic UseAs low As$2.09 $2.09 - $3.29
90ML Urine Test Cup 16 Panel with ETG, FEN, K2, TRA & Adulterants
ADLTX, AMP, BAR, BUP, BZO, COC, EtG, FEN, K2, MDMA, MET, MTD, OPI/MOR, OXY, PCP, THC, TRAForensic UseAs low As$1.99 $1.99 - $3.29
16 Panel Urine Test Cup detects ADLX, TRA, K2, FEN & ETG, As low as $1.79
ADLTX, AMP, BAR, BUP, BZO, COC, EtG, FEN, K2, MDMA, MET, MTD, OPI/MOR, OXY, PCP, THC, TRAForensic UseAs low As$1.79 $1.79 - $2.99
CLIA Waived 16 Panel Drug Test Cup, detects Fentanyl 1ng, PPX, TCA and TML FDA Approved – As low as $1.99
AMP, BAR, BUP, BZO, COC, MDMA, MET, MTD, OPI/MOR, OXY, PCP, PPX, TCA, THC, FEN 1ng/ml, TRACLIA WAIVEDAs low As$1.99 $1.99 - $3.39Features of Our 16 Panel Drug Test Cups
Every 16 panel cup in this range shares six features:
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- Sixteen drugs, one cup: Collect and test in one step, with no dipping.
- Results in about 5 minutes: Read the cup within the time limit in the package insert.
- Temperature strip: Fresh urine reads 90–100°F within 4 minutes of collection.
- Double click-top lid: Leak-resistant for storage or for sending a non-negative sample to a lab.
- Two sizes: 120 mL standard and 90 mL economy.
- Clear status on every label: One cup is CLIA waived for point-of-care testing; six are Forensic Use Only. Check each product.
What Does a 16 Panel Drug Test Cup Detect?
A 16 panel drug test cup detects sixteen drugs or drug classes, but there is no single standard list. Lab 16 panels often add drugs such as meperidine or carisoprodol, while instant cups like ours add alcohol, fentanyl and newer drugs. The first table shows every strip used across our seven cups. The second table matches each cup to its drug set.
Strips in our 16 panel cups
| Strip | Substance | Cutoff (ng/mL) | What it picks up | In how many of 7 cups |
|---|---|---|---|---|
|
Amphetamines | 1000 (500 on the CLIA cup) | Adderall, Vyvanse | 7 |
|
Barbiturates | 300 | Butalbital, phenobarbital | 7 |
|
Buprenorphine | 10 | Suboxone, Subutex | 7 |
|
Benzodiazepines | 300 | Xanax, Valium, Klonopin | 7 |
|
Cocaine | 300 (150 on the CLIA cup) | Powder cocaine, crack | 7 |
|
Fentanyl | 20 (1 on the CLIA cup) | Fentanyl; not caught by opiate strips | 7 |
|
Ecstasy | 500 | Ecstasy, Molly | 7 |
|
Methamphetamine | 1000 (500 on the CLIA cup) | Crystal meth | 7 |
|
Methadone | 300 | Methadone treatment | 7 |
|
Opiates (morphine) | 300 (2000 on two 90 mL cups) | Heroin, morphine, codeine | 7 |
|
Oxycodone | 100 | OxyContin, Percocet | 7 |
|
Phencyclidine | 25 | Angel dust | 7 |
|
Marijuana | 50 | Cannabis, edibles, vapes | 6 |
|
Ethyl glucuronide (alcohol) | 300 | Recent drinking | 6 |
|
Tramadol | 100 | Ultram | 5 |
|
Synthetic cannabinoids | 50 | Spice, K2 | 4 |
|
Tricyclic antidepressants | 1000 | Amitriptyline, nortriptyline | 3 |
|
Kratom | 500 | Mitragynine | 2 |
|
Ketamine | 1000 | Ketamine | 1 |
|
Propoxyphene | 300 | Darvon (withdrawn) | 1 |
|
Adulterant checks | — | Diluted or tampered samples | 4 |
Choose your 16 panel cup
| Cup | What it adds to the 12 core drugs | Size | Status | From |
|---|---|---|---|---|
| Kratom, EtG and TCA cup | THC, EtG, kratom, TCA | 120 mL | Forensic Use Only | $1.99 |
| Tramadol, EtG and TCA cup | THC, EtG, tramadol, TCA | 120 mL | Forensic Use Only | $1.99 |
| CLIA-waived fentanyl 1 ng/mL cup | THC, tramadol, TCA, propoxyphene; no EtG | 120 mL | CLIA waived | $1.99 |
| K2, tramadol and EtG cup with adulterant checks | THC, EtG, tramadol, K2 + pH/SG/CR | 120 mL | Forensic Use Only | $1.69 |
| 90 mL K2 and tramadol economy cup | Same drug set as the 120 mL K2 cup + pH/SG/CR | 90 mL | Forensic Use Only | $1.99 |
| 90 mL ketamine and K2 economy cup | THC, EtG, K2, ketamine + pH/SG/CR | 90 mL | Forensic Use Only | $1.99 |
| 90 mL THC-free kratom, K2 and tramadol cup | EtG, tramadol, K2, kratom; no THC | 90 mL | Forensic Use Only | $1.99 |
Single-box prices start at $3.29 (90 mL) and $3.39 (120 mL) for 25 cups. Treat any non-negative result as preliminary and confirm it by GC-MS or LC-MS/MS before acting. Need gabapentin too? See our 17 panel cups. Need one strip fewer? Compare our 15 panel cups.
How to Use a 16 Panel Drug Test Cup
A 16 panel cup is used in three steps, then read with three possible results:
Step 1 – Collect
Open the sealed pouch just before use. The donor fills the cup to the line. Close the lid until it clicks.
Step 2 – Check temperature
Within 4 minutes, check that the temperature strip reads 90–100°F. Set the cup on a flat surface.
Step 3 – Read
Peel off the label and read at 5 minutes. Don't read after the time limit in the insert.
Positive
Only the control line (C) appears. The drug is at or above the cutoff. This is a preliminary result; confirm it by GC-MS or LC-MS/MS.
Negative
Lines appear at C and T. A faint T line still counts as negative.
Invalid
No C line. Retest with a new cup. If it happens again, call us at 561-897-9238 with the lot number.
What Is in a 16 Panel Multi-Drug Test Cup, Class by Class?
A 16 panel cup is the step up from a 12 or 14 panel when your program needs alcohol, fentanyl and newer drugs on the same screen. These are the five drug classes our cups cover:
-
Opioids – five or six strips:
Opiates (OPI), oxycodone (OXY), methadone (MTD), buprenorphine (BUP) and fentanyl (FEN) on every cup, plus tramadol (TRA) on 5 cups. Opiate strips don't reliably detect oxycodone, fentanyl or tramadol, which is why each has its own strip. Read more about tramadol and drug testing.
-
Stimulants:
Amphetamines (AMP), methamphetamine (MET), cocaine (COC) and MDMA, on every cup.
-
Sedatives, antidepressants and dissociatives:
Benzodiazepines (BZO), barbiturates (BAR) and PCP on every cup; tricyclic antidepressants (TCA) on 3; ketamine (KET) on 1. A BZO strip doesn't detect barbiturates, so both are included.
-
Cannabis, synthetic drugs and kratom:
Marijuana (THC 50) on 6 cups, K2/Spice on 4, kratom on 2. Our THC-free 90 mL cup suits programs that allow medical cannabis but monitor everything else.
-
Alcohol and specimen validity:
EtG (300 ng/mL) on 6 cups shows recent drinking, not current intoxication. pH, specific gravity and creatinine on 4 cups flag samples outside normal ranges, which can point to dilution or tampering. Recollect a flagged sample, under observation if your policy allows.
Every cup has a temperature strip and built-in control lines.
16 Panel Cups Direct From the Manufacturer
- › In-house antibodies:
We make the antibodies used in our lateral flow test strips, so we control quality from strip to finished Serenity Cup®.
- › Tamper-evident and leak-resistant:
A sealed pouch, a tamper-evident seal and a double click-top lid. - › Temperature strip on every cup:
A reading outside 90–100°F within 4 minutes points to a substituted or cooled sample. - › Results in about 5 minutes:
Two lines = negative; control line only = preliminary positive. Confirm positives at a lab.
- › Built for volume:
90 mL economy cups lower the cost per test for corrections and high-volume programs. - › Always in stock:
US warehouse stock, same-day shipping before 3:00 PM EST, free shipping on 100+ cups.
Bulk, OEM and private label:
561-897-9238 · [email protected]
Send your current supplier's price list and we'll beat it by 10%.
Private Label 16 Panel Cups
Our OEM and private label program puts your brand on any of the seven 16 panel cups:
- › Your logo on the cup label, pouch and box
- › A drug set and cutoffs that fit your market (EtG, fentanyl, tramadol, K2, kratom, ketamine, TCA, adulterant checks; 120 or 90 mL)
- › Tiered wholesale pricing plus the 10% beat-your-quote promise
- › Drop shipping under your brand from US stock
- › One account rep for distributors, clinics, MAT programs, courts and corrections
Learn how our reseller and wholesale program works, or call 561-897-9238.
Bulk Pricing that Cuts the Budget in Half
Priority Shipping For Bulk Orders.
Dedicated Wholesale Representative.
Quality That Is Reliable For the Nation.
Why 16 Panel Cups Add EtG, Fentanyl & K2
Older 10 and 12 panel cups miss three things many treatment and court programs now ask about: drinking, fentanyl and synthetic drugs.
- › EtG is a breakdown product of alcohol that stays in urine longer than alcohol itself. How long depends on how much was drunk and on the cutoff. See how long EtG stays in urine.
- › Fentanyl is a synthetic opioid that standard opiate strips don't reliably detect, so it needs its own strip. All seven cups have one.
- › K2 (Spice) is a group of synthetic cannabinoids that THC strips don't detect. Four cups add a K2 strip.
Where 16 Panel Cups Are Used
Five settings use 16 panel cups most; this table matches each to a cup:
| Setting | Main uses | Best-fit 16 panel cup | Why |
|---|---|---|---|
| Probation, parole and drug courts | Random compliance testing, phase reviews | K2/tramadol cups with adulterant checks | Fentanyl, alcohol, K2 and tamper checks on one screen. Confirm non-negatives at a lab before they are used as evidence. |
| Sober living | Admission and routine screening | Kratom/EtG cup or THC-free kratom cup | Alcohol and kratom on the same cup. |
| MAT and behavioral health | BUP/MTD adherence, relapse checks | Tramadol/EtG cup, kratom/EtG cup | Separate BUP, MTD, OXY, FEN and TRA strips show prescribed treatment drugs next to illicit opioids. |
| Pain management clinics | Opioid adherence | CLIA-waived fentanyl cup | CLIA waived, fentanyl at 1 ng/mL, tramadol and TCA strips. |
| Corrections | Intake, random, post-visit | 90 mL economy cups | Lower cost per test at high volume. |
Are 16 Panel Cups Right for Workplace Testing?
Sometimes. Most non-DOT employers use a 5 to 12 panel cup. A 16 panel cup fits workplaces with a specific need, such as a policy that covers fentanyl, tramadol or alcohol. DOT-regulated tests can't use instant cups; they must go to an HHS-certified lab under 49 CFR Part 40. For a lower-cost workplace panel, compare our 14 panel cups.
16 Panel Cups for Probation, Courts and Treatment Programs
Probation departments, drug courts and treatment programs use 16 panel cups because one cup covers fentanyl, alcohol (EtG) and synthetic drugs as well as the classic drug classes. That saves a second test when someone is suspected of drinking or using K2.
- › Court-ordered and random compliance screening
- › Fentanyl, EtG and K2 on one screen
- › Adulterant checks at collection on four cups
- › A preliminary result in about 5 minutes. Positives should be confirmed at a lab before sanctions, as many courts require.
Treatment and MAT programs use the same cups to check that patients take buprenorphine or methadone as prescribed and to spot relapse. A 16 panel dip card is an option for programs that collect in their own cups.
Trust in 12 Panel Now. Leading Supplier of Drug Tests in The US
Best Rates
We beat any written quote by 10%
Priority allocation
Stock reserved for bulk and contract buyers
Fast Shipping
Same day before 3:00 PM EST, free on 100+ cups
Multi Drug Test Options
350+ configurations, 5 to 28 panels
Best Customer Service
Dedicated Sales Representative For Our Customers
CLIA Waived vs Forensic Use Only: What's the Difference?
The 16 panel drug test urine cup carries a "Forensic Use Only" designation, which has specific meaning for who can purchase it and how results can be used.
- CLIA waived: The FDA has cleared the test and categorized it as waived under CLIA. Sites with a CLIA certificate of waiver can run it at the point of care. It is still a screening test, and positives should be confirmed at a lab. One of our 16 panel cups is CLIA waived: the fentanyl 1 ng/mL cup. See all CLIA waived drug tests.
- Forensic Use Only: The product has not gone through FDA 510(k) clearance for clinical use. It is sold for forensic settings such as courts, probation, corrections and compliance programs. It is not for diagnosis, treatment decisions or home use. Six of our 16 panel cups are Forensic Use Only.
-
-
- How results are used: Forensic tests check program compliance, for example probation conditions or sober living rules. Many courts require lab confirmation (GC-MS or LC-MS/MS) before a screening result is used as evidence.
-
Request Volume Pricing
Tell us your monthly volume and drug list, and we'll quote tiered pricing in writing. Contact our sales team or call 561-897-9238.
Place Your Order
Order 16 panel cups online or through your account rep. Same-day shipping on orders placed before 3:00 PM EST.
Frequently Asked Questions for 16 Panel Drug Test Cups
16 panel drug test cup is used for rapid urine screening in probation programs, workplaces, rehabilitation centers, and forensic testing to detect multiple drugs and alcohol metabolites in a single test.
It typically detects AMP, BAR, BZO, BUP, COC, MET, OPI, OXY, PCP, MDMA, THC, MTD, KET, K2, FEN, and ETG.
Yes, most modern 16 panel drug test cups include a dedicated fentanyl (FEN) strip designed to detect synthetic opioid exposure.
They provide presumptive screening accuracy using immunoassay technology, but any positive result is typically confirmed with laboratory testing such as GC/MS.
Yes, it includes ETG (Ethyl Glucuronide), which detects recent alcohol consumption beyond the detection window of breathalyzers.
Fentanyl is generally detectable for 2–3 days depending on dosage, frequency of use, and metabolism.
ETG is a metabolite of alcohol that allows detection of alcohol consumption for up to 80 hours in urine.
Yes, it can detect prescription opioids, benzodiazepines, buprenorphine, methadone, and oxycodone.bstance coverage or for individuals conducting self-screening.
It uses immunoassay test strips inside a sealed cup that react to drug metabolites in urine, producing visible results within minutes.
A 16 panel test includes expanded detection for fentanyl, ETG alcohol, ketamine, and synthetic cannabinoids, which are not included in most 12 panel tests.
Yes, 16 panel drug tests with a K2 strip can detect synthetic cannabinoid metabolites.
THC detection identifies marijuana use through urine metabolites, with detection times varying based on usage frequency.
Yes, they are widely used for court-ordered testing, compliance monitoring, and relapse detection in probation and parole systems.
Yes, many expanded panels include ketamine (KET), a dissociative anesthetic increasingly seen in forensic testing.
A positive result indicates the presence of a drug metabolite above the cutoff level, but confirmation testing is recommended.
Most instant urine drug test cups provide results within 5 minutes after sample collection.
Yes, which is why many 16 panel drug test cups include adulteration checks such as pH, creatinine, and specific gravity testing.
A cutoff level is the minimum concentration of a drug metabolite required to trigger a positive result in a screening test.
Yes, they are commonly used in safety-sensitive industries for pre-employment, random, and post-incident drug screening.
